
盛南(Sheng Nan)
長聘教軌副教授
Email: shengnan@sjtu.edu.cn
研究方向
1. 新型環境汙染物的危害識別和高通量篩查
2. 新型環境汙染物毒性效應的分子機製研究
3. 環境汙染物與生物大分子的相互作用及其生物毒性效應
個人簡歷
2018年於中國科意昂4動物研究所獲得理學博士學位;2018-2020年,於中國科意昂4動物研究所開展博士後研究🦸♀️,研究工作包括🧧:新型多氟及全氟烷基化合物對小鼠的肝臟毒性及機製、多氟及全氟化合物與關鍵生物大分子間的相互作用。
2020年至今,意昂4体育平台🧚🏿♂️,長聘教軌助理教授
代表性論著
1. Sheng N, Wang J, Guo Y, Wang J and Dai J. Interactions of perfluorooctanesulfonate (PFOS) and 6:2 chlorinated polyfluorinated ether sulfonate (6:2 Cl-PFESA) with human serum albumin (HSA): A comparative study [J]. Chemical Research in Toxicology. 2020, 33(6): 1478-1486.
2. Sheng N, Pan Y, Guo Y, Sun Y and Dai J. Hepatotoxic effects of hexafluoropropylene oxide trimer acid (HFPO-TA), a novel perfluorooctanoic acid (PFOA) alternative, on mice at low dosage exposure[J]. Environmental Science & Technology. 2018, 52(14):8005-8015.
3. Sheng N, Cui R, Wang J, Guo Y, Wang J and Dai J. Cytotoxicity of novel fluorinated alternatives to long-chain perfluoroalkyl substances to human liver cell line and their binding capacity to human liver fatty acid binding protein[J]. Archives of Toxicology. 2018, 92(1):359-369.(高被引論文)
4. Sheng N, Zhou X, Zheng F, Pan Y, Guo X, Guo Y, Sun Y and Dai J. Comparative hepatotoxicity of 6:2 fluorotelomer carboxylic acid and 6:2 fluorotelomer sulfonic acid, two fluorinated alternatives to long-chain perfluoroalkyl acids, on adult male mice[J]. Archives of Toxicology. 2017, 91(8):2909-2919.
5. Sheng N, Li J, Liu H, Zhang A and Dai J. Interaction of perfluoroalkyl acids with human liver fatty acid-binding protein[J]. Archives of Toxicology. 2016, 90(1):217-27.
6. Zhang W1, Sheng N1, Wang M, Zhang H and Dai J. Zebrafish reproductive toxicity induced by chronic perfluorononanoate exposure[J]. Aquatic Toxicology. 2016, 175:269-76.
研究成果
1. 基於分子與蛋白相互作用的新型全氟聚醚羧酸在小鼠體內分布機製研究 (青年科學基金項目: 21906160)